Application of the Phenomenological Model to Electrophoretic Mobility in Mixed Solvent Electrolyte Systems in Capillary Zone Electrophoresis

The phenomenological model of Khossravi and Connors (1992) has been adopted to calculate the electrophoretic mobility of drugs at different concentrations of solvents in a binary mixture. The accuracy and predictability of the model have been evaluated employing 14 experimental data sets by using average percentage mean deviation (APMD). The obtained APMD for correlative and predictive studies are within an acceptable error range and the results show that the model can be used in method development stage to speed up the optimisation process.